(E)-2-(4-isopropylstyryl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane - Names and Identifiers
| Name | (E)-2-(4-isopropylstyryl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
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| Synonyms | (E)-2-(4-isopropylstyryl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
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(E)-2-(4-isopropylstyryl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane - Introduction
(E)-2-(4-isopropylstylyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is an Organoboron compound commonly abbreviated as TBDMSB. Its properties are as follows:
1. Appearance: TBDMSB is a colorless to yellow liquid.
2. Melting point: The melting point of TBDMSB is -30 ° C.
3. Boiling Point: the boiling point of TBDMSB is 105-108 ° C.
4. Density: The density of TBDMSB is 0.846 g/mL.
5. Solubility: TBDMSB is soluble in non-polar organic solvents, such as ether, petroleum ether and dichloromethane.
TBDMSB is mainly used as a reagent and intermediate in organic synthesis. Specific applications include the following:
1. Protecting group: TBDMSB can form a temporary protecting group by reacting with boron-acid ester and other active functional groups such as hydroxyl.
2. Boron and silicon Source: TBDMSB contains boron and silicon atoms, which can be used as the source of these two elements.
3. Catalyst for chemical reactions: TBDMSB can be used as a catalyst to participate in organic synthesis reactions, such as boron etherification reaction and boron-silicon bond activation reaction.
The preparation of TBDMSB can usually be carried out through the following steps:
1. First, allyl alcohol is reacted with 4-isopropylbenzaldehyde to obtain (E)-2-(4-isopropylstyryl) ethanol.
2. Then, by reacting (E)-2-(4-isopropylstyryl) ethanol with sodium hydroxide and sodium tetramethylborohydride, the target product TBDMSB is obtained.
Regarding the safety information of TBDMSB, it is a chemical and needs to be operated safely. Here are some common security measures:
1. Avoid contact with eyes, skin and taking.
2. Appropriate protective measures should be used during operation, such as wearing chemical goggles, protective gloves and laboratory coats.
3. Operate in a well-ventilated place to avoid inhaling vapors.
4. If you come into contact with TBDMSB, immediately flush the affected area with plenty of water and seek medical help immediately.
5. Before using TBDMSB, carefully read and follow the safety data sheet and operation manual provided by the manufacturer.
Last Update：2024-04-09 21:01:54